When my daughter was born 22 years ago, my mom was living with us and going through chemo treatments. The pediatrician recommended holding off on the polio vaccine as mom could possibly contract it from my daughter shedding the vaccine. We held off a few months. Otherwise both my daughters were kept to their vaccine schedule, including gardasil.
When my nephew was born a micro premie 8 years ago, he spent 4 months in the hospital and came home with a feeding tube. My sister requested the family (8 siblings in total, spouses, nieces and nephews along with BIL's parents and family) all make sure our vaccines were up to date if we wanted to hold him. Another sister and a niece smoked, my sister asked that they not only wash up prior to visiting but change clothes into clean ones that had not been smoked in. My nephew had lung problems at that time.
We all complied. I went and received my booster. The two who smoked up the opportunity as a kick in the pants to quit smoking. Both went to a hypnotist and have not smoked since.
Being asked about up to date vaccination didn't phase any of us as we knew it was in the best interests of our nephew.