It's not unsafe, but it's a huge pain. If you're getting a rental car, it's extra super annoying. It's been several years since we've flown in to LAX so maybe it has changed, but I remember standing in a line at the rental counter, then standing in a line waiting for a shuttle, then standing in line again at the actual rental location, then waiting in line in our rental car to leave the lot. It was a good 90 minutes from getting off the plane to driving off in our rental car. Then you have a long drive and the areas area around the airport isn't great. We don't even consider flying in to LAX any more and would rather pay more to fly into SNA.