Maybe.
If the restaurant is owned by Disney, then yes, they'll take DDP and GCs in all cases. If it's not owned by Disney, generally, restaurants in DS that accept DDP also accept Disney Gift Cards. However, they pop in and out of acceptings DDP and Disney Gift Cards all the time. A restaurant could for a couple of months, and then suddenly decide they no longer wish to take them.
Best thing to do is to call the restaurants you're interested in and ask.
OP just giving you our experiences but we used the GC at Raglan Road, Cooke's, WPE and the old Fulton's. We have eat at WPE every trip and have used them on the last 5 or 6 visits.you are staying at a WDW resort you can charge to the room then go and use GC at the resort to pay down the balance. Just make sure you have a backup in case the GC system is down. Happened to us at Ghiradelli's but since it was for an ice cream and I had cash & also a CC it wasn't an issue.